Faculty of Public Health and Health CareBook 8.4 · Medical and Clinical Diagnostic Activities

FRI-2G.309-1-MCDA-02

ISCHEMIC STROKE - CURRENT THERAPEUTIC STRATEGIES AND PREVENTION

Assoc. Prof. Neli Petrova, MD, PhD

Department of Medical Clinical and Diagnostical Activities University of Ruse “Angel Kanchev”

Abstract

Stroke is one of the top three leading causes of death and disability worldwide, affecting around 12 million people a year and resulting in 6.6 million deaths. Ischaemic stroke is a major public health priority and will become increasingly relevant to neurologists of the future. The cornerstone of effective stroke care continues to be timely reperfusion treatment. This requires early recognition of symptoms by the public and first responders, triage to an appropriate stroke centre and efficient assessment and investigation by the attending stroke team. The aim of treatment is to achieve recanalisation and reperfusion of the ischaemic penumbra with intravenous thrombolysis and/or endovascular thrombectomy in appropriately selected patients. All patients should be admitted directly to an acute stroke unit for close monitoring for early neurological deterioration and prevention of secondary complications. Prompt investigation of the mechanism of stroke allows patients to start appropriate secondary preventative treatment.

Keywords

Ischemic stroke, Thrombolysis, Endovascular thrombectomy, Stroke unit

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